Rhodamine dyes square measure wide used as fluorescent probes thanks to their highly visible light quantum yield and photo-stability. though minute quantities of significant metal ions square measure necessary for the living organisms. They play important roles in biological, environmental, and chemical systems, however, excessive amounts have a harmful impact on the organisms. the event of chemo-sensor for sensing and recognition of environmentally and biologically vital ions. The probes square measure priceless for the dynamics of organic phenomenon, supermolecule expression, and molecular interactions in advanced living systems. they're usually used as scaffolds in biological labeling and stimulant visible-light imaging. This book mentioned within the context of the structural options of rhodamine derivatives organized in keeping with their fluorescent core scaffold and with their representative applications.